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Ultrafast lasers enable rapid cancer diagnosis with simultaneous two and three-photon imaging
Higher-order harmonic generation (HHG) microscopy enables rapid, label-free visualization of unprocessed tissue – transforming cancer diagnosis during procedures like bronchoscopy. Traditional histopathological analysis requires days to deliver results, often necessitating repeat procedures when biopsies prove inconclusive.
This white paper explores how compact ultrafast laser systems capable of simultaneous two- and three-photon microscopy can provide diagnostic feedback in just six minutes, offering immediate clinical decisions while the patient is still in the operating room.
Key learnings:
- How sub-40 femtosecond pulses enable four nonlinear imaging modalities simultaneously—2PF, SHG, 3PF, and THG
- Clinical applications for rapid intraoperative tissue analysis with 87% diagnostic accuracy
- Advantages of compact fiber-based femtosecond lasers for bringing advanced microscopy from research labs into clinical settings
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Physics Today and Wiley are proud to bring you this white paper, sponsored by HÜBNER Photonics.
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HÜBNER Photonics offers a full range of high performance lasers and terahertz systems including single and multi-line Cobolt lasers, tunable C-WAVE lasers, C-FLEX laser combiners, VALO femtosecond fiber lasers and Terahertz imagers and spectrometers.
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