How Charged Aerosol Detection is
Revolutionizing HPLC Analysis

Article Collection

Traditional detection methods such as UV-Vis and MS have limitations when you need to analyze a complex mixture of compounds, such as those that lack a chromophore or are not ionizable. The Charged Aerosol Detector (CAD) can help you extract valuable information about sample composition that is not always possible with traditional methods. HPLC-CAD analysis is a powerful alternative that offers you sensitive, near-universal detection and standard-free quantitation. This analytical technique is an invaluable tool for industry professionals, especially those in the pharmaceutical and natural medicine fields.

This article collection aims to give you information on the benefits of using HPLC-CAD analysis, allowing you to gain a deeper understanding of sample composition, and further your research in this field.

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What you will learn about:

  • Charged aerosol detection of lipid nanoparticles
  • Quantification of linear polyethylenimines
  • Chemical compositions of medicinal plants
  • CAD method development tips
  • Benefits of HPLC-CAD analysis


Articles contained in the collection:

  • Determination of lipid content and stability in lipid nanoparticles using ultra high-performance liquid chromatography in combination with a Corona Charged Aerosol Detector. (Kinsey et al.)
  • Development of an ultra-high-performance liquid chromatography-charged aerosol detection/UV method for the quantitation of linear polyethylenimines in oligonucleotide polyplexes. (Socia et al.)
  • Quality analysis of hawthorn leaves (the leaves of Crataegus pinnatifida Bge. var major N.E.Br) in different harvest time. (Zheng et al.)
  • Quantitative and qualitative investigations of pharmacopoeial plant material polygoni avicularis herba by UHPLC-CAD and UHPLC-ESI-MS methods. (Granica et al.)

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