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This Expert Insights eBook hopes to provide scientists with more information on analytical ultracentrifugation (AUC), allowing you to further your research in this field.
What you will learn about:
- The role of AUC in biotherapeutic research
- Innovations in AUC technology
- Case studies on the application of AUC in therapeutic strategies
- Insights from key opinion leaders (KOLs) around the utility of AUC for drug discovery
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More Information
Analytical ultracentrifugation (AUC) serves as a vital technique in drug discovery and characterization, providing critical insights into the characterization of macromolecules such as proteins, viral vectors, lipid nanoparticles (LNPs), and other biological assemblies. Recent innovations in AUC technology have enhanced its precision, efficiency, and applicability, making it an indispensable tool for bioanalysis. This Expert Insights explores the transformative impact of modern AUC techniques on biotherapeutic research, highlighting its role in addressing contemporary challenges and driving innovation.
Articles contained in the collection:
- McAlpine et al. (2024). Structural and biophysical characterisation of ubiquitin variants that inhibit the ubiquitin conjugating enzyme Ube2d2. The FEBS Journal. https://doi.org/10.1111/febs.17311.
- Erlandsen et al. (2022). NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2. FEBS Letters. https://doi.org/10.1002/1873-3468.14276.