Wiley Current Protocols

CRISPR and the Revolution of Cancer Research

CRISPR is a gene-editing technology that has revolutionized the field of cancer research by enabling scientists to make precise, targeted changes to the genome and study the role of individual genes in cancer development. It is being used to create personalized cancer therapies and to develop new treatments and animal models to test potential therapies. Through CRISPR, researchers are exploring how to best prevent and treat cancer, potentially leading to improved patient outcomes.


This article collection hopes to provide researchers with more information on these techniques and technologies, allowing them to further their research in this field. 


What you will learn:  

  • CRISPR-Cas9 gene-editing technology.
  • Safety and efficacy of CRISPR-based therapies.
  • How to improve treatments for aggressive diseases.
  • The advantages and limitations of CRISPR-Cas9.

Articles contained in the collection:

  • Exploiting the CRISPR-Cas9 gene-editing system for human cancers and immunotherapy. (Afolabi et al.)
  • Strengthening the CAR-T cell therapeutic application using CRISPR/Cas9 technology. (Sadeqi Nezhad et al.)
  • CRISPR/Cas9 technology as a potent molecular tool for gene therapy. (Karimian et al.)
  • How to monitor and minimize off-target events during genome editing. (Application note)
  • Advancing CAR T cell therapy with CTS TrueCut Cas9 Protein. (Application note)

Download this complimentary article collection today!  

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