Emerging infectious disease is a rising area of focus for global health. In the last 50 years, over 40 new diseases have emerged globally. To understand and develop interventions for novel infectious diseases, researchers need to obtain insights into mechanisms such as pathogen infection and replication, host immune response, and post-infection immune status. To achieve these ends, scientists employ technologies such as advanced flow cytometry, ligand-based antibody binding assays, and live cell imaging and analysis to gain meaningful insights that allow for the rapid development of therapeutics.
This Expert Insights publication provides an overview of recent advances in research for emerging infectious diseases. The studies include descriptions regarding advances in scaffold platforms for identifying novel mimetic ligands for blocking viral binding and the development of novel methods for detection of antibodies from patient samples.
What you will learn:
- Antibody development and diagnostic pathways
- Approaches for studying host-pathogen life cycle
- Technological platforms for infectious disease research
- Engineering Defensin α-Helix to Produce High-Affinity SARS-CoV-2 Spike Protein Binding Ligands
- A Functional Assay for Serum Detection of Antibodies Against SARS-CoV-2 Nucleoprotein
- Evaluating Viral Infections Across the Entire Host-Pathogen Life Cycle
- Advanced Flow Cytometry Applications in Infectious Disease and Immuno-Oncology