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This resource will accelerate your research by providing proven LC-MS methodologies and workflows that enhance protein characterization accuracy, improve biotherapeutic quality control, and enable deeper analysis of complex biomolecules.
What you will learn about:
- ECD fundamentals
- Multidimensional antibody characterization workflows
- Advanced LC-MS applications in biotherapeutics
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This Expert Insights eBook explores recent breakthroughs in LC-MS technology for peptide and protein analysis, featuring comprehensive summaries of Electron Capture Dissociation (ECD) techniques for deep protein characterization and advanced multidimensional workflows for resolving monoclonal antibody charge variants in biotherapeutic development.
Article digests:
- Cooper, H.J. et al. (2005). The role of electron capture dissociation in biomolecular analysis. Mass Spectrometry Reviews. https://doi.org/10.1002/mas.20014.
- Sarin, D. et al. (2024). Offline Coupling of Hydrophobic Interaction Chromatography–Capillary Zone Electrophoresis for Monitoring Charge‐Based Heterogeneity of Recombinant Monoclonal Antibodies. ELECTROPHORESIS. https://doi.org/10.1002/elps.202400158
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